15.10.2026

Reid Hoffman is leaving Microsoft’s board to go ‘founder mode’ with startup Manus

After a really worthwhile decade on Microsoft’s board, Reid Hoffman is stepping down, the corporate introduced Thursday. Hoffman joined the board after Microsoft purchased his firm LinkedIn for $26.2 billion in 2016.

Hoffman was on Microsoft’s board when it invested its first $1 billion into OpenAI in 2019. Hoffman was one in every of OpenAI’s authentic traders and served on the mannequin maker’s board till he stepped down in 2023, citing too many potential conflicts of curiosity to proceed. He was additionally on Microsoft’s board when the tech large entered into a kind of non-acquisition, acqui-hire offers for $650 million together with his AI startup Inflection AI. Microsoft employed Inflection co-founder Mustafa Suleyman by way of that deal.

Hoffman stated on a latest episode of his “Doable” podcast, whereas speaking with Microsoft CEO Satya Nadella, that he’s able to go “founder mode” together with his newest AI startup, Manus. Manus is a drug discovery firm that raised over $50 million by way of a few seed rounds final 12 months. Hoffman is an investor, as is Basic Catalyst.

Hoffman is cited as a co-founder of Manus and chairman of the board, not the CEO, although. That job belongs to Dr. Siddhartha Mukherjee, a doctor, biologist, and Pulitzer Prize-winning creator of the 2011 e book “The Emperor of All Maladies: A Biography of Most cancers.”

Nonetheless, Hoffman stated he’s excited to present Manus extra consideration.

“One of many issues I noticed over the past month was that, we’re seeing such progress with Manus. I must get again to founder mode,” he stated. He believes the startup is making progress on “Transfer 37” AI, that means AI that supersedes human creativity in chemistry, particularly to fight numerous cancers, he added.

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